2F64
Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.6 A resolution with 1-METHYLQUINOLIN-2(1H)-ONE bound
Summary for 2F64
Entry DOI | 10.2210/pdb2f64/pdb |
Related | 2A0K 2F2T 2F62 2F67 |
Descriptor | Nucleoside 2-deoxyribosyltransferase, SULFATE ION, 1-METHYLQUINOLIN-2(1H)-ONE, ... (5 entities in total) |
Functional Keywords | sgpp, structural genomics, psi, protein structure initiative ndrt, nucleoside 2-deoxyribosyltransferase, trypanosoma brucei, structural genomics of pathogenic protozoa consortium, transferase |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 2 |
Total formula weight | 38022.82 |
Authors | Bosch, J.,Robien, M.A.,Hol, W.G.J.,Structural Genomics of Pathogenic Protozoa Consortium (SGPP) (deposition date: 2005-11-28, release date: 2005-12-06, Last modification date: 2023-11-15) |
Primary citation | Bosch, J.,Robien, M.A.,Mehlin, C.,Boni, E.,Riechers, A.,Buckner, F.S.,Van Voorhis, W.C.,Myler, P.J.,Worthey, E.A.,DeTitta, G.,Luft, J.R.,Lauricella, A.,Gulde, S.,Anderson, L.A.,Kalyuzhniy, O.,Neely, H.M.,Ross, J.,Earnest, T.N.,Soltis, M.,Schoenfeld, L.,Zucker, F.,Merritt, E.A.,Fan, E.,Verlinde, C.L.,Hol, W.G.J. Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. J.Med.Chem., 49:5939-5946, 2006 Cited by PubMed: 17004709DOI: 10.1021/jm060429m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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