2F62

Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.5 A resolution with (2-ETHYLPHENYL)METHANOL bound

Summary for 2F62

• Entry DOI: 10.2210/pdb2f62/pdb
• Related: 2A0K 2F2T 2F64 2F67
• Descriptor: Nucleoside 2-deoxyribosyltransferase, SULFATE ION, (2-ETHYLPHENYL)METHANOL, ... (5 entities in total)
• Functional Keywords: sgpp, structural genomics, psi, protein structure initiative ndrt, nucleoside 2-deoxyribosyltransferase, trypanosoma brucei, structural genomics of pathogenic protozoa consortium, transferase
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 38072.89

Authors

Bosch, J.,Robien, M.A.,Hol, W.G.J.,Structural Genomics of Pathogenic Protozoa Consortium (SGPP) (deposition date: 2005-11-28, release date: 2005-12-06, Last modification date: 2023-11-15)

• Primary citation: Bosch, J.,Robien, M.A.,Mehlin, C.,Boni, E.,Riechers, A.,Buckner, F.S.,Van Voorhis, W.C.,Myler, P.J.,Worthey, E.A.,DeTitta, G.,Luft, J.R.,Lauricella, A.,Gulde, S.,Anderson, L.A.,Kalyuzhniy, O.,Neely, H.M.,Ross, J.,Earnest, T.N.,Soltis, M.,Schoenfeld, L.,Zucker, F.,Merritt, E.A.,Fan, E.,Verlinde, C.L.,Hol, W.G.J.; Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.; J.Med.Chem., 49:5939-5946, 2006; PubMed: 17004709; DOI: 10.1021/jm060429m

Experimental method

X-RAY DIFFRACTION (1.5 Å)