2ESA
GRP94 n-terminal domain bound to geldanamycin: effects of mutants 168-169 KS-AA
Summary for 2ESA
Entry DOI | 10.2210/pdb2esa/pdb |
Related | 1QY5 1TBW 1TC0 1TC6 1U2O 1YT1 |
Descriptor | Endoplasmin, GELDANAMYCIN, TETRAETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | grp94 gp96 hsp90 bergerat chaperone endoplasmic reticulum geldanamycin 17-aag, chaperone |
Biological source | Canis lupus familiaris (dog) More |
Cellular location | Endoplasmic reticulum lumen: P41148 |
Total number of polymer chains | 1 |
Total formula weight | 27495.12 |
Authors | Immormino, R.M.,Metzger IV, L.E.,Gewirth, D.T. (deposition date: 2005-10-25, release date: 2006-10-03, Last modification date: 2023-08-23) |
Primary citation | Immormino, R.M.,Metzger IV, L.E.,Reardon, P.N.,Gewirth, D.T. Crystal Structure of GRP94 with the specific mutation KS168-169AA; with bound Geldanamycin To be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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