2EC8
Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit
Summary for 2EC8
Entry DOI | 10.2210/pdb2ec8/pdb |
Related | 1EXZ 2E9W |
Descriptor | Mast/stem cell growth factor receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
Functional Keywords | glycoprotein, receptor tyrosine kinase, growth factor cytokine, dimerization, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 60160.47 |
Authors | Yuzawa, S.,Opatowsky, Y.,Zhang, Z.,Mandiyan, V.,Lax, I.,Schlessinger, J. (deposition date: 2007-02-11, release date: 2007-08-07, Last modification date: 2020-07-29) |
Primary citation | Yuzawa, S.,Opatowsky, Y.,Zhang, Z.,Mandiyan, V.,Lax, I.,Schlessinger, J. Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor Cell(Cambridge,Mass.), 130:323-334, 2007 Cited by PubMed: 17662946DOI: 10.1016/j.cell.2007.05.055 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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