Crystal structure of human MD-2

Summary for 2E56

DescriptorLymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, MYRISTIC ACID, ... (4 entities in total)
Functional Keywordsinnate immunity, lipid-binding, lipid binding protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space Q9Y6Y9
Total number of polymer chains1
Total molecular weight17713.66
Ohto, U.,Satow, Y. (deposition date: 2006-12-19, release date: 2007-06-26, Last modification date: 2011-07-13)
Primary citation
Ohto, U.,Fukase, K.,Miyake, K.,Satow, Y.
Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa.
Science, 316:1632-1634, 2007
PubMed: 17569869 (PDB entries with the same primary citation)
DOI: 10.1126/science.1139111
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.253182.1%3.0%5.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2e56
no rotation
Molmil generated image of 2e56
rotated about x axis by 90°
Molmil generated image of 2e56
rotated about y axis by 90°