2E56

Crystal structure of human MD-2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001530	molecular_function	lipopolysaccharide binding
A	0035662	molecular_function	Toll-like receptor 4 binding
A	0045087	biological_process	innate immune response

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Region: {"description":"Interaction with lipopolysaccharide","evidences":[{"source":"PubMed","id":"17569869","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17803912","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2E56","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E59","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4G8A","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"17569869","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2E56","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E59","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---