2DSQ

Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins

2DSQ の概要

• エントリーDOI: 10.2210/pdb2dsq/pdb
• 関連するPDBエントリー: 1WQJ 2DSP 2DSR
• 分子名称: Insulin-like growth factor-binding protein 4, Insulin-like growth factor IB, Insulin-like growth factor-binding protein 1 (3 entities in total)
• 機能のキーワード: igf, igfbp, insulin, protein binding-hormone-growth factor complex, protein binding/hormone/growth factor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P22692 P05019 P08833
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 56737.09

構造登録者

Sitar, T.,Popowicz, G.M.,Siwanowicz, I.,Huber, R.,Holak, T.A. (登録日: 2006-07-05, 公開日: 2006-08-22, 最終更新日: 2023-10-25)

• 主引用文献: Sitar, T.,Popowicz, G.M.,Siwanowicz, I.,Huber, R.,Holak, T.A.; Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins.; Proc.Natl.Acad.Sci.Usa, 103:13028-13033, 2006; PubMed: 16924115; DOI: 10.1073/pnas.0605652103

実験手法

X-RAY DIFFRACTION (2.8 Å)