2CLT

Crystal structure of the active form (full-length) of human fibroblast collagenase.

2CLT の概要

• エントリーDOI: 10.2210/pdb2clt/pdb
• 関連するPDBエントリー: 1AYK 1CGE 1CGF 1CGL 1HFC 1SU3 2AYK 2TCL 3AYK 4AYK 966C
• 分子名称: INTERSTITIAL COLLAGENASE, CALCIUM ION, ZINC ION, ... (4 entities in total)
• 機能のキーワード: extracellular matrix, fibroblast collagenase, zinc, calcium, zymogen, protease, collagen, autocatalytic cleavage, matrix metalloproteinases, hydrolase, polymorphism, glycoprotein, metal-binding, inhibitor-free, metalloprotease, collagen degradation
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Secreted, extracellular space, extracellular matrix (Probable): P03956
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 85042.40

構造登録者

Iyer, S.,Visse, R.,Nagase, H.,Acharya, K.R. (登録日: 2006-04-29, 公開日: 2006-08-09, 最終更新日: 2023-12-13)

• 主引用文献: Iyer, S.,Visse, R.,Nagase, H.,Acharya, K.R.; Crystal Structure of an Active Form of Human Mmp-1.; J.Mol.Biol., 362:78-, 2006; PubMed: 16890240; DOI: 10.1016/J.JMB.2006.06.079

実験手法

X-RAY DIFFRACTION (2.67 Å)