2CJZ
crystal structure of the c472s mutant of human protein tyrosine phosphatase ptpn5 (step, striatum enriched phosphatase) in complex with phosphotyrosine
Summary for 2CJZ
Entry DOI | 10.2210/pdb2cjz/pdb |
Related | 2BIJ 2BV5 |
Descriptor | HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5, O-PHOSPHOTYROSINE, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | protein phosphatase, step, ptpn5, hydrolase, phosphatase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 35512.01 |
Authors | Debreczeni, J.E.,Barr, A.J.,Eswaran, J.,Smee, C.,Burgess, N.,Gileadi, O.,Savitsky, P.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,Knapp, S.,von Delft, F. (deposition date: 2006-04-10, release date: 2006-05-16, Last modification date: 2023-12-13) |
Primary citation | Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.F.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S. Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome. Cell(Cambridge,Mass.), 136:352-, 2009 Cited by PubMed: 19167335DOI: 10.1016/J.CELL.2008.11.038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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