2CJZ

crystal structure of the c472s mutant of human protein tyrosine phosphatase ptpn5 (step, striatum enriched phosphatase) in complex with phosphotyrosine

Summary for 2CJZ

Entry DOI	10.2210/pdb2cjz/pdb
Related	2BIJ 2BV5
Descriptor	HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5, O-PHOSPHOTYROSINE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	protein phosphatase, step, ptpn5, hydrolase, phosphatase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	35512.01
Authors	Debreczeni, J.E.,Barr, A.J.,Eswaran, J.,Smee, C.,Burgess, N.,Gileadi, O.,Savitsky, P.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,Knapp, S.,von Delft, F. (deposition date: 2006-04-10, release date: 2006-05-16, Last modification date: 2023-12-13)
Primary citation	Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.F.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S. Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome. Cell(Cambridge,Mass.), 136:352-, 2009 Cited by PubMed: 19167335 DOI: 10.1016/J.CELL.2008.11.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation