2CJZ

crystal structure of the c472s mutant of human protein tyrosine phosphatase ptpn5 (step, striatum enriched phosphatase) in complex with phosphotyrosine

2CJZ の概要

• エントリーDOI: 10.2210/pdb2cjz/pdb
• 関連するPDBエントリー: 2BIJ 2BV5
• 分子名称: HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5, O-PHOSPHOTYROSINE, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: protein phosphatase, step, ptpn5, hydrolase, phosphatase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35512.01

構造登録者

Debreczeni, J.E.,Barr, A.J.,Eswaran, J.,Smee, C.,Burgess, N.,Gileadi, O.,Savitsky, P.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,Knapp, S.,von Delft, F. (登録日: 2006-04-10, 公開日: 2006-05-16, 最終更新日: 2023-12-13)

• 主引用文献: Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.F.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S.; Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome.; Cell(Cambridge,Mass.), 136:352-, 2009; PubMed: 19167335; DOI: 10.1016/J.CELL.2008.11.038

実験手法

X-RAY DIFFRACTION (1.7 Å)