2CFI
The hydrolase domain of human 10-FTHFD in complex with 6- formyltetrahydropterin
Summary for 2CFI
Entry DOI | 10.2210/pdb2cfi/pdb |
Related | 2BW0 2CQ8 |
Descriptor | 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, SULFATE ION, 6-FORMYLTETRAHYDROPTERIN, ... (4 entities in total) |
Functional Keywords | tetrahydrofolate, folate binding, nadp, one-carbon metabolism, oxidoreductase, phosphopantetheine |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: O75891 |
Total number of polymer chains | 1 |
Total formula weight | 36866.86 |
Authors | Kursula, P.,Stenmark, P.,Arrowsmith, C.,Edwards, A.,Ehn, M.,Graslund, S.,Hammarstrom, M.,Hallberg, M.,Kotenyova, T.,Nilsson-Ehle, P.,Nordlund, P.,Ogg, D.J.,Persson, C.,Sagemark, J.,Schuler, H.,Sundstrom, M.,Thorsell, A.,Weigelt, J. (deposition date: 2006-02-21, release date: 2006-03-14, Last modification date: 2023-12-13) |
Primary citation | Kursula, P.,Schuler, H.,Flodin, S.,Nilsson-Ehle, P.,Ogg, D.J.,Savitsky, P.,Nordlund, P.,Stenmark, P. Structures of the Hydrolase Domain of Human 10-Formyltetrahydrofolate Dehydrogenase and its Complex with a Substrate Analogue. Acta Crystallogr.,Sect.D, 62:1294-, 2006 Cited by PubMed: 17057331DOI: 10.1107/S0907444906026849 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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