2CFI
The hydrolase domain of human 10-FTHFD in complex with 6- formyltetrahydropterin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE | polymer | 329 | 36383.5 | 1 | UniProt (O75891) Pfam (PF00551) Pfam (PF02911) In PDB | HOMO SAPIENS (HUMAN) | 10-FTHFDH, ALDEHYDE DEHYDROGENASE 1 FAMILY MEMBER L1 |
2 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
3 | A | 6-FORMYLTETRAHYDROPTERIN | non-polymer | 195.2 | 1 | Chemie (ZZZ) | |||
4 | water | water | 18.0 | 303 | Chemie (HOH) |
Sequence modifications
A: 1 - 307 (UniProt: O75891)
PDB | External Database | Details |
---|---|---|
Met -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
Ser -14 | - | expression tag |
Ser -13 | - | expression tag |
Gly -12 | - | expression tag |
Val -11 | - | expression tag |
Asp -10 | - | expression tag |
Leu -9 | - | expression tag |
Gly -8 | - | expression tag |
Thr -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 36383.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 483.4 | |
All* | Total formula weight | 36866.9 |