2BIY
Structure of PDK1-S241A mutant kinase domain
Summary for 2BIY
Entry DOI | 10.2210/pdb2biy/pdb |
Related | 1H1W 1OKY 1OKZ 1UU3 1UU7 1UU8 1UU9 1UVR 1W1D 1W1G 1W1H |
Descriptor | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, SULFATE ION, ... (5 entities in total) |
Functional Keywords | agc kinase, ac-helix, atp-binding, phosphorylation, phosphoinositide dependent protein kinase, pi3-kinase signalling, pif-pocket, pka, pkb, t-loop mutant, serine-threonine-protein kinase, transferase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 37226.99 |
Authors | Komander, D.,Kular, G.S.,Deak, M.,Alessi, D.R.,van Aalten, D.M.F. (deposition date: 2005-01-26, release date: 2005-02-23, Last modification date: 2023-12-13) |
Primary citation | Komander, D.,Kular, G.,Deak, M.,Alessi, D.R.,van Aalten, D.M. Role of T-loop phosphorylation in PDK1 activation, stability, and substrate binding. J. Biol. Chem., 280:18797-18802, 2005 Cited by PubMed: 15741170DOI: 10.1074/jbc.M500977200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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