2BHJ

murine iNO synthase with coumarin inhibitor

Summary for 2BHJ

Entry DOI	10.2210/pdb2bhj/pdb
Related	1DD7 1DF1 1DWV 1DWW 1DWX 1JWJ 1JWK 1M8D 1M8E 1M8H 1M8I 1M9T 1N2N 1NOC 1NOD 1NOS 1QOM 1QW4 1QW5 1R35 1VAF 2NOD 2NOS 3NOD
Descriptor	NITRIC OXIDE SYNTHASE, THIOCOUMARIN, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
Functional Keywords	inos, calmodulin-binding, fad, fmn, heme, metal-binding, nadp, oxidoreductase, polymorphism, zinc
Biological source	MUS MUSCULUS (MOUSE)
Total number of polymer chains	1
Total formula weight	49988.59
Authors	Mathieu, M.,Guilloteau, J.P. (deposition date: 2005-01-12, release date: 2005-03-31, Last modification date: 2023-12-13)
Primary citation	Jackson, S.A.,Sahni, S.,Lee, L.,Luo, Y.,Nieduzak, T.R.,Liang, G.,Chiang, Y.,Collar, N.,Fink, D.,He, W.,Laoui, A.,Merrill, J.,Boffey, R.,Crackett, P.,Rees, B.,Wong, M.,Guilloteau, J.P.,Mathieu, M.,Rebello, S.S. Design, Synthesis and Characterization of a Novel Class of Coumarin-Based Inhibitors of Inducible Nitric Oxide Synthase Bioorg.Med.Chem., 13:2723-, 2005 Cited by PubMed: 15781384 DOI: 10.1016/J.BMC.2005.02.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation