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1VAF

Inducible nitric oxide synthase oxygenase domain complexed with the inhibitor AR-R17477

Summary for 1VAF
Entry DOI10.2210/pdb1vaf/pdb
Related1QW4 1QW5 1QW6 1QWC 1VAG
DescriptorNitric oxide synthase, inducible, ZINC ION, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
Functional Keywordsmurine inosoxy inhibitor complex, oxidoreductase
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total formula weight99582.44
Authors
Fedorov, R.,Vasan, R.,Ghosh, D.K.,Schlichting, I. (deposition date: 2004-02-16, release date: 2004-06-01, Last modification date: 2023-10-25)
Primary citationFedorov, R.,Vasan, R.,Ghosh, D.K.,Schlichting, I.
Structures of nitric oxide synthase isoforms complexed with the inhibitor AR-R17477 suggest a rational basis for specificity and inhibitor design
Proc.Natl.Acad.Sci.USA, 101:5892-5897, 2004
Cited by
PubMed: 15071192
DOI: 10.1073/pnas.0306588101
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

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