2BBZ

Crystal Structure of MC159 Reveals Molecular Mechanism of DISC Assembly and vFLIP Inhibition

Summary for 2BBZ

• Entry DOI: 10.2210/pdb2bbz/pdb
• Related: 2BBR
• Descriptor: Viral CASP8 and FADD-like apoptosis regulator (2 entities in total)
• Functional Keywords: death effector domain, viral protein
• Biological source: Molluscum contagiosum virus subtype 1
• Total number of polymer chains: 4
• Total formula weight: 112155.73

Authors

Yang, J.K.,Wang, L.,Zheng, L.,Wan, F.,Ahmed, M.,Lenardo, M.J.,Wu, H. (deposition date: 2005-10-18, release date: 2006-02-14, Last modification date: 2024-02-14)

• Primary citation: Yang, J.K.,Wang, L.,Zheng, L.,Wan, F.,Ahmed, M.,Lenardo, M.J.,Wu, H.; Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition.; Mol.Cell, 20:939-949, 2005; PubMed: 16364918; DOI: 10.1016/j.molcel.2005.10.023

Experimental method

X-RAY DIFFRACTION (3.8 Å)