2BBT

Human deltaF508 NBD1 with two solublizing mutations.

Summary for 2BBT

• Entry DOI: 10.2210/pdb2bbt/pdb
• Related: 2BBO 2BBS
• Descriptor: Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: atp binding cassette, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 65950.67

Authors

Lewis, H.A.,Kearins, M.C.,Conners, K.,Zhao, X.,Lu, F.,Sauder, J.M.,Emtage, S. (deposition date: 2005-10-17, release date: 2005-11-01, Last modification date: 2023-08-23)

• Primary citation: Lewis, H.A.,Wang, C.,Zhao, X.,Hamuro, Y.,Conners, K.,Kearins, M.C.,Lu, F.,Sauder, J.M.,Molnar, K.S.,Coales, S.J.,Maloney, P.C.,Guggino, W.B.,Wetmore, D.R.,Weber, P.C.,Hunt, J.F.; Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.; J.Mol.Biol., 396:406-430, 2010; PubMed: 19944699; DOI: 10.1016/j.jmb.2009.11.051

Experimental method

X-RAY DIFFRACTION (2.3 Å)