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2B9S

Crystal Structure of heterodimeric L. donovani topoisomerase I-vanadate-DNA complex

Summary for 2B9S
Entry DOI10.2210/pdb2b9s/pdb
Descriptor5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', 5'-D(*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', ... (7 entities in total)
Functional Keywordstopoisomerase i, vanadate complex, isomerase-dna complex, isomerase/dna
Biological sourceLeishmania donovani
More
Total number of polymer chains5
Total formula weight71607.03
Authors
Davies, D.R.,Hol, W.G.J. (deposition date: 2005-10-12, release date: 2006-01-17, Last modification date: 2024-02-14)
Primary citationDavies, D.R.,Mushtaq, A.,Interthal, H.,Champoux, J.J.,Hol, W.G.
The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA.
J.Mol.Biol., 357:1202-1210, 2006
Cited by
PubMed: 16487540
DOI: 10.1016/j.jmb.2006.01.022
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.27 Å)
Structure validation

217705

건을2024-03-27부터공개중

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