Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2B9S

Crystal Structure of heterodimeric L. donovani topoisomerase I-vanadate-DNA complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003917molecular_functionDNA topoisomerase type I (single strand cut, ATP-independent) activity
A0005694cellular_componentchromosome
A0006265biological_processDNA topological change
B0003677molecular_functionDNA binding
B0003917molecular_functionDNA topoisomerase type I (single strand cut, ATP-independent) activity
B0005694cellular_componentchromosome
B0006265biological_processDNA topological change
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE VO4 B 301
ChainResidue
AARG314
AARG410
AHIS453
BTYR222
BHOH303
CDT10
DDA11

Functional Information from PROSITE/UniProt
site_idPS00176
Number of Residues19
DetailsTOPO_IB_1 Topoisomerase (Topo) IB-type active site signature. DnkavslGTSKinYIdprI
ChainResidueDetails
BASP209-ILE227

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon