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2B9S

Crystal Structure of heterodimeric L. donovani topoisomerase I-vanadate-DNA complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3'polymer103061.11
2B
(D)
5'-D(*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3'polymer123684.51
3C
(E)
5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3'polymer226705.41
4D
(A)
topoisomerase I-like proteinpolymer43250903.01GenBank (5305782)
Pfam (PF02919)
Pfam (PF01028)
UniProt (by SIFTS) (Q9GPZ9)
Leishmania donovani
5E
(B)
DNA topoisomerase I-like proteinpolymer627138.21GenBank (17528932)
Pfam (PF14370)
UniProt (by SIFTS) (Q8WQM6)
Leishmania donovani
6F
(B)
VANADATE IONnon-polymer114.91Chemie (VO4)
7G, H, I, J, K
(C, D, E, A, B)
waterwater18.0130Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight71492.1
Non-Polymers*Number of molecules1
Total formula weight114.9
All*Total formula weight71607.0
*Water molecules are not included.

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PDB entries from 2025-07-30

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