2B4J
Structural basis for the recognition between HIV-1 integrase and LEDGF/p75
Summary for 2B4J
Entry DOI | 10.2210/pdb2b4j/pdb |
Related | 1ITG 1K6Y 1z9e |
Descriptor | Integrase (IN), PC4 and SFRS1 interacting protein, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | hiv, integration, transcription, viral protein, recombination |
Biological source | Human immunodeficiency virus 1 More |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P12497 Nucleus : O75475 |
Total number of polymer chains | 4 |
Total formula weight | 59524.24 |
Authors | Cherepanov, P.,Ambrosio, A.L.,Rahman, S.,Ellenberger, T.,Engelman, A. (deposition date: 2005-09-24, release date: 2005-10-25, Last modification date: 2023-08-23) |
Primary citation | Cherepanov, P.,Ambrosio, A.L.,Rahman, S.,Ellenberger, T.,Engelman, A. Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75 Proc.Natl.Acad.Sci.Usa, 102:17308-17313, 2005 Cited by PubMed: 16260736DOI: 10.1073/pnas.0506924102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
Download full validation report