1ITG
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES
Summary for 1ITG
Entry DOI | 10.2210/pdb1itg/pdb |
Descriptor | HIV-1 INTEGRASE, CACODYLATE ION (3 entities in total) |
Functional Keywords | dna integration, dna binding (viral) |
Biological source | Human immunodeficiency virus 1 |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497 |
Total number of polymer chains | 1 |
Total formula weight | 18468.74 |
Authors | Dyda, F.,Hickman, A.B.,Jenkins, T.M.,Engelman, A.,Craigie, R.,Davies, D.R. (deposition date: 1994-11-21, release date: 1995-05-08, Last modification date: 2024-02-07) |
Primary citation | Dyda, F.,Hickman, A.B.,Jenkins, T.M.,Engelman, A.,Craigie, R.,Davies, D.R. Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. Science, 266:1981-1986, 1994 Cited by PubMed: 7801124PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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