2AX6

Crystal Structure Of The Androgen Receptor Ligand Binding Domain T877A Mutant In Complex With Hydroxyflutamide

Summary for 2AX6

Entry DOI	10.2210/pdb2ax6/pdb
Related	1Z95 2ax7 2ax8 2ax9 2axa
Descriptor	Androgen receptor, HYDROXYFLUTAMIDE (3 entities in total)
Functional Keywords	transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus : P10275
Total number of polymer chains	1
Total formula weight	30131.14
Authors	Bohl, C.E.,Miller, D.D.,Chen, J.,Bell, C.E.,Dalton, J.T. (deposition date: 2005-09-03, release date: 2005-09-20, Last modification date: 2023-08-23)
Primary citation	Bohl, C.E.,Miller, D.D.,Chen, J.,Bell, C.E.,Dalton, J.T. Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor J.Biol.Chem., 280:37747-37754, 2005 Cited by PubMed: 16129672 DOI: 10.1074/jbc.M507464200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation