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2AX6

Crystal Structure Of The Androgen Receptor Ligand Binding Domain T877A Mutant In Complex With Hydroxyflutamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Androgen receptorpolymer25629838.91UniProt (P10275)
Pfam (PF00104)
Homo sapiens (human)
2B
(A)
HYDROXYFLUTAMIDEnon-polymer292.21Chemie (HFT)
3C
(A)
waterwater18.0200Chemie (HOH)
Sequence modifications
A: 664 - 919 (UniProt: P10275)
PDBExternal DatabaseDetails
Ala 877Thr 876engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29838.9
Non-Polymers*Number of molecules1
Total formula weight292.2
All*Total formula weight30131.1
*Water molecules are not included.

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PDB entries from 2025-10-15

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