Crystal structure of the archaeal box H/ACA sRNP Nop10-Cbf5 complex

Summary for 2AUS

Descriptorpseudouridine synthase, Ribosome biogenesis protein Nop10, PHOSPHATE ION, ... (5 entities in total)
Functional Keywordsisomerase, structural protein, isomerase-structural protein complex, isomerase/structural protein
Biological sourcePyrococcus abyssi
Total number of polymer chains4
Total molecular weight90561.2
Charron, C.,Manival, X.,Charpentier, B.,Fourmann, J.-B.,Godard, F.,Branlant, C. (deposition date: 2005-08-29, release date: 2006-07-11, Last modification date: 2017-10-11)
Primary citation
Manival, X.,Charron, C.,Fourmann, J.B.,Godard, F.,Charpentier, B.,Branlant, C.
Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity
Nucleic Acids Res., 34:826-839, 2006
PubMed: 16456033 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gkj482
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25290.4%1.3%8.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report