2AUS

Crystal structure of the archaeal box H/ACA sRNP Nop10-Cbf5 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000495	biological_process	box H/ACA sno(s)RNA 3'-end processing
A	0001522	biological_process	pseudouridine synthesis
A	0003723	molecular_function	RNA binding
A	0006396	biological_process	RNA processing
A	0008033	biological_process	tRNA processing
A	0009451	biological_process	RNA modification
A	0009982	molecular_function	pseudouridine synthase activity
A	0016853	molecular_function	isomerase activity
A	0031118	biological_process	rRNA pseudouridine synthesis
A	0031119	biological_process	tRNA pseudouridine synthesis
A	0031120	biological_process	snRNA pseudouridine synthesis
A	0106029	molecular_function	tRNA pseudouridine synthase activity
A	1990481	biological_process	mRNA pseudouridine synthesis
B	0001522	biological_process	pseudouridine synthesis
B	0006364	biological_process	rRNA processing
B	0030515	molecular_function	snoRNA binding
B	0031118	biological_process	rRNA pseudouridine synthesis
B	0031120	biological_process	snRNA pseudouridine synthesis
B	0042254	biological_process	ribosome biogenesis
B	0070034	molecular_function	telomerase RNA binding
B	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
B	1990904	cellular_component	ribonucleoprotein complex
C	0000495	biological_process	box H/ACA sno(s)RNA 3'-end processing
C	0001522	biological_process	pseudouridine synthesis
C	0003723	molecular_function	RNA binding
C	0006396	biological_process	RNA processing
C	0008033	biological_process	tRNA processing
C	0009451	biological_process	RNA modification
C	0009982	molecular_function	pseudouridine synthase activity
C	0016853	molecular_function	isomerase activity
C	0031118	biological_process	rRNA pseudouridine synthesis
C	0031119	biological_process	tRNA pseudouridine synthesis
C	0031120	biological_process	snRNA pseudouridine synthesis
C	0106029	molecular_function	tRNA pseudouridine synthase activity
C	1990481	biological_process	mRNA pseudouridine synthesis
D	0001522	biological_process	pseudouridine synthesis
D	0006364	biological_process	rRNA processing
D	0030515	molecular_function	snoRNA binding
D	0031118	biological_process	rRNA pseudouridine synthesis
D	0031120	biological_process	snRNA pseudouridine synthesis
D	0042254	biological_process	ribosome biogenesis
D	0070034	molecular_function	telomerase RNA binding
D	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
D	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 1070

Chain	Residue
B	CYS8
B	CYS11
B	CYS20
B	CYS23

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 1071

Chain	Residue
D	CYS8
D	CYS11
D	CYS20
D	CYS23

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 D 1001

Chain	Residue
D	GLU43
D	ARG46
D	ARG50
D	HOH140
C	GLU229

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 B 1002

Chain	Residue
A	HIS225
A	GLU229
B	GLU43
B	ARG46
B	ARG50
B	HOH1083

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 A 1003

Chain	Residue
A	GLY79
A	THR80
A	LYS108
A	ALA176
A	GLY177
A	ARG202
A	HOH1022
A	HOH1073

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 C 1004

Chain	Residue
C	LYS108
C	TYR110
C	GLY177
C	ARG202

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 B 1006

Chain	Residue
A	HIS218
B	ARG34
B	SER36
B	ASP39
B	PRO40
B	HOH1072
B	HOH1076

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_01081

Chain	Residue	Details
C	ASP82
A	ASP82

---