2AUS
Crystal structure of the archaeal box H/ACA sRNP Nop10-Cbf5 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000495 | biological_process | box H/ACA sno(s)RNA 3'-end processing |
| A | 0001522 | biological_process | pseudouridine synthesis |
| A | 0003723 | molecular_function | RNA binding |
| A | 0006396 | biological_process | RNA processing |
| A | 0008033 | biological_process | tRNA processing |
| A | 0009451 | biological_process | RNA modification |
| A | 0009982 | molecular_function | pseudouridine synthase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0031118 | biological_process | rRNA pseudouridine synthesis |
| A | 0031119 | biological_process | tRNA pseudouridine synthesis |
| A | 0031120 | biological_process | snRNA pseudouridine synthesis |
| A | 0160148 | molecular_function | tRNA pseudouridine(55) synthase activity |
| A | 1990481 | biological_process | mRNA pseudouridine synthesis |
| B | 0001522 | biological_process | pseudouridine synthesis |
| B | 0006364 | biological_process | rRNA processing |
| B | 0030515 | molecular_function | snoRNA binding |
| B | 0042254 | biological_process | ribosome biogenesis |
| B | 1990904 | cellular_component | ribonucleoprotein complex |
| C | 0000495 | biological_process | box H/ACA sno(s)RNA 3'-end processing |
| C | 0001522 | biological_process | pseudouridine synthesis |
| C | 0003723 | molecular_function | RNA binding |
| C | 0006396 | biological_process | RNA processing |
| C | 0008033 | biological_process | tRNA processing |
| C | 0009451 | biological_process | RNA modification |
| C | 0009982 | molecular_function | pseudouridine synthase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0031118 | biological_process | rRNA pseudouridine synthesis |
| C | 0031119 | biological_process | tRNA pseudouridine synthesis |
| C | 0031120 | biological_process | snRNA pseudouridine synthesis |
| C | 0160148 | molecular_function | tRNA pseudouridine(55) synthase activity |
| C | 1990481 | biological_process | mRNA pseudouridine synthesis |
| D | 0001522 | biological_process | pseudouridine synthesis |
| D | 0006364 | biological_process | rRNA processing |
| D | 0030515 | molecular_function | snoRNA binding |
| D | 0042254 | biological_process | ribosome biogenesis |
| D | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1070 |
| Chain | Residue |
| B | CYS8 |
| B | CYS11 |
| B | CYS20 |
| B | CYS23 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1071 |
| Chain | Residue |
| D | CYS8 |
| D | CYS11 |
| D | CYS20 |
| D | CYS23 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 D 1001 |
| Chain | Residue |
| D | GLU43 |
| D | ARG46 |
| D | ARG50 |
| D | HOH140 |
| C | GLU229 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1002 |
| Chain | Residue |
| A | HIS225 |
| A | GLU229 |
| B | GLU43 |
| B | ARG46 |
| B | ARG50 |
| B | HOH1083 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1003 |
| Chain | Residue |
| A | GLY79 |
| A | THR80 |
| A | LYS108 |
| A | ALA176 |
| A | GLY177 |
| A | ARG202 |
| A | HOH1022 |
| A | HOH1073 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 C 1004 |
| Chain | Residue |
| C | LYS108 |
| C | TYR110 |
| C | GLY177 |
| C | ARG202 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1006 |
| Chain | Residue |
| A | HIS218 |
| B | ARG34 |
| B | SER36 |
| B | ASP39 |
| B | PRO40 |
| B | HOH1072 |
| B | HOH1076 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 150 |
| Details | Domain: {"description":"PUA","evidences":[{"source":"HAMAP-Rule","id":"MF_01081","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_01081","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ze1 |
| Chain | Residue | Details |
| C | ASP82 | |
| C | TYR110 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ze1 |
| Chain | Residue | Details |
| A | ASP82 | |
| A | TYR110 |
