2ABZ

Crystal structure of C19A/C43A mutant of leech carboxypeptidase inhibitor in complex with bovine carboxypeptidase A

Summary for 2ABZ

• Entry DOI: 10.2210/pdb2abz/pdb
• Related: 1DTD 1DTV 1ZFL
• Descriptor: Carboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION (3 entities in total)
• Functional Keywords: inhibitor-metallocarboxypeptidase complex, lci mutant, oxidative folding intermediate analog, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Bos taurus (cattle); More
• Cellular location: Secreted, extracellular space: P00730
• Total number of polymer chains: 6
• Total formula weight: 98906.82

Authors

Arolas, J.L.,Popowicz, G.M.,Bronsoms, S.,Aviles, F.X.,Huber, R.,Holak, T.A.,Ventura, S. (deposition date: 2005-07-18, release date: 2006-01-31, Last modification date: 2021-11-10)

• Primary citation: Arolas, J.L.,Popowicz, G.M.,Bronsoms, S.,Aviles, F.X.,Huber, R.,Holak, T.A.,Ventura, S.; Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond; J.Mol.Biol., 352:961-975, 2005; PubMed: 16126224; DOI: 10.1016/j.jmb.2005.07.065

Experimental method

X-RAY DIFFRACTION (2.16 Å)