2A26

Crystal structure of the N-terminal, dimerization domain of Siah Interacting Protein

Summary for 2A26

• Entry DOI: 10.2210/pdb2a26/pdb
• Related: 2a25
• Descriptor: Calcyclin-binding protein, SULFATE ION, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ... (4 entities in total)
• Functional Keywords: helical hairpin, dimerization, apoptosis
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q9HB71
• Total number of polymer chains: 3
• Total formula weight: 17746.58

Authors

Santelli, E.,Leone, M.,Li, C.,Fukushima, T.,Preece, N.E.,Olson, A.J.,Ely, K.R.,Reed, J.C.,Pellecchia, M.,Liddington, R.C.,Matsuzawa, S. (deposition date: 2005-06-21, release date: 2005-08-09, Last modification date: 2024-02-14)

• Primary citation: Santelli, E.,Leone, M.,Li, C.,Fukushima, T.,Preece, N.E.,Olson, A.J.,Ely, K.R.,Reed, J.C.,Pellecchia, M.,Liddington, R.C.,Matsuzawa, S.; Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex; J.Biol.Chem., 280:34278-34287, 2005; PubMed: 16085652; DOI: 10.1074/jbc.M506707200

Experimental method

X-RAY DIFFRACTION (1.2 Å)