2Z81
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Summary for 2Z81
Entry DOI | 10.2210/pdb2z81/pdb |
Related | 2Z7X 2Z80 2Z82 |
Descriptor | Toll-like receptor 2, Variable lymphocyte receptor B, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | tlr2, pam3csk4, lipopeptide, innate immunity, cytoplasmic vesicle, glycoprotein, immune response, inflammatory response, leucine-rich repeat, membrane, receptor, transmembrane, immune system |
Biological source | Mus musculus (house mouse, inshore hagfish) More |
Total number of polymer chains | 1 |
Total formula weight | 64263.73 |
Authors | |
Primary citation | Jin, M.S.,Kim, S.E.,Heo, J.Y.,Lee, M.E.,Kim, H.M.,Paik, S.G.,Lee, H.,Lee, J.O. Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide Cell(Cambridge,Mass.), 130:1071-1082, 2007 Cited by PubMed: 17889651DOI: 10.1016/j.cell.2007.09.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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