2Z80
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Summary for 2Z80
Entry DOI | 10.2210/pdb2z80/pdb |
Related | 2Z7X 2Z81 2Z82 |
Descriptor | Toll-like receptor 2, Variable lymphocyte receptor B, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | tlr2, lipopeptide, innate immunity, glycoprotein, immune response, inflammatory response, leucine-rich repeat, membrane, receptor, transmembrane, immune system |
Biological source | Homo sapiens (human, inshore hagfish) More |
Total number of polymer chains | 2 |
Total formula weight | 79641.52 |
Authors | |
Primary citation | Jin, M.S.,Kim, S.E.,Heo, J.Y.,Lee, M.E.,Kim, H.M.,Paik, S.G.,Lee, H.,Lee, J.O. Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide Cell(Cambridge,Mass.), 130:1071-1082, 2007 Cited by PubMed: 17889651DOI: 10.1016/j.cell.2007.09.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report