2WKR

Structure of a photoactivatable Rac1 containing the Lov2 C450M Mutant

Summary for 2WKR

Entry DOI	10.2210/pdb2wkr/pdb
Related	1E96 1FOE 1G4U 1HE1 1HH4 1I4D 1I4L 1I4T 1MH1 1RYF 1RYH 2FJU 2V0U 2V0W 2V1A 2V1B 2VRW 2WKP 2WKQ
Descriptor	NPH1-1, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, GUANOSINE-5'-TRIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ... (6 entities in total)
Functional Keywords	transferase, cell adhesion, nucleotide-binding, protein engineering, ras superfamily lov2, phototropin1, protein design, small g-protein, light-induced signal transduction, gtpase, rho family, atp-binding, prenylation, chimera, nucleotide-binding protein engineering, adp-ribosylation
Biological source	AVENA SATIVA (OAT) More
Cellular location	Cell membrane ; Lipid-anchor ; Cytoplasmic side : P63000
Total number of polymer chains	1
Total formula weight	38705.77
Authors	Wu, Y.I.,Frey, D.,Lungu, O.I.,Jaehrig, A.,Schlichting, I.,Kuhlman, B.,Hahn, K.M. (deposition date: 2009-06-16, release date: 2009-08-18, Last modification date: 2023-12-13)
Primary citation	Wu, Y.I.,Frey, D.,Lungu, O.I.,Jaehrig, A.,Schlichting, I.,Kuhlman, B.,Hahn, K.M. A Genetically Encoded Photoactivatable Rac Controls the Motility of Living Cells. Nature, 461:104-, 2009 Cited by PubMed: 19693014 DOI: 10.1038/NATURE08241 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation