2WKR
Structure of a photoactivatable Rac1 containing the Lov2 C450M Mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NPH1-1, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 | polymer | 332 | 37631.0 | 1 | UniProt (O49003) UniProt (P63000) Pfam (PF00071) | AVENA SATIVA (OAT) | P21-RAC1, RAS-LIKE PROTEIN TC25, CELL MIGRATION-INDUCING GENE 5 PROTEIN |
| 2 | B (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 3 | C (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) PubChem (710) PubChem (8965) PubChem (643976) PubChem (5702760) PubChem (7048779) PubChem (7048781) PubChem (23585816) PubChem (51435500) PubChem (51435503) PubChem (15559251) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 5 | E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 6 | G (A) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A: 404 - 546 (UniProt: O49003)
A: 547 - 723 (UniProt: P63000)
| PDB | External Database | Details |
|---|---|---|
| Met 450 | Cys 450 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 392 | - | expression tag |
| Arg 393 | - | expression tag |
| Gly 394 | - | expression tag |
| Ser 395 | - | expression tag |
| His 396 | - | expression tag |
| His 397 | - | expression tag |
| His 398 | - | expression tag |
| His 399 | - | expression tag |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
| Gly 402 | - | expression tag |
| Ser 403 | - | expression tag |
| Leu 604 | Gln 61 | engineered mutation |
| His 634 | Glu 91 | engineered mutation |
| His 635 | Asn 92 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37631.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1074.7 | |
| All* | Total formula weight | 38705.8 |
