2OXW

Human MMP-12 complexed with the peptide IAG

Summary for 2OXW

Entry DOI	10.2210/pdb2oxw/pdb
Related	1RMZ 1Y93 2OXU 2OXZ 2OY2 2OY4
Descriptor	Macrophage metalloelastase, ILE-ALA-GLY peptide, ZINC ION, ... (5 entities in total)
Functional Keywords	mmp-12, matrix metalloproteinase, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted, extracellular space, extracellular matrix (Probable): P39900
Total number of polymer chains	2
Total formula weight	18126.02
Authors	Calderone, V.,Bertini, I.,Fragai, M.,Luchinat, C.,Maletta, M.,Yeo, K.J. (deposition date: 2007-02-21, release date: 2007-03-06, Last modification date: 2023-08-30)
Primary citation	Bertini, I.,Calderone, V.,Fragai, M.,Luchinat, C.,Maletta, M.,Yeo, K.J. Snapshots of the reaction mechanism of matrix metalloproteinases. ANGEW.CHEM.INT.ED.ENGL., 45:7952-7955, 2006 Cited by PubMed: 17096442 DOI: 10.1002/anie.200603100 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.15 Å)

Structure validation