2KJU

NMR structure of human insulin mutant glu-b21-d-glu, his-b10 asp pro-b28-lys, lys-b29-pro, 20 structures

Summary for 2KJU

• Entry DOI: 10.2210/pdb2kju/pdb
• Related: 2KJJ
• Descriptor: Insulin (2 entities in total)
• Functional Keywords: hormone, human insulin, mutant, fibrillation, stability, carbohydrate metabolism, cleavage on pair of basic residues, disulfide bond, glucose metabolism, secreted, diabetes mellitus, disease mutation, pharmaceutical, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01308 P01308
• Total number of polymer chains: 2
• Total formula weight: 5794.59

Authors

Hua, Q.X.,Huang, K.,Hu, S.Q.,Katsoyanni, P.,Weiss, M.A. (deposition date: 2009-06-10, release date: 2010-06-16, Last modification date: 2021-10-13)

• Primary citation: Hua, Q.X.,Huang, K.,Hu, S.Q.,Katsoyanni, P.,Weiss, M.A.; Acceleration of Protein Fibrillation by Chiral Destabilization of Beta-Turn; To be Published,

Experimental method

SOLUTION NMR