2GYS

2.7 A structure of the extracellular domains of the human beta common receptor involved in IL-3, IL-5, and GM-CSF signalling

Summary for 2GYS

Entry DOI	10.2210/pdb2gys/pdb
Related	1gh7
Descriptor	Cytokine receptor common beta chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	dimer of interlocking chains of fibronectin-iii domains, four fibronectin-iii domains per chain, signaling protein, cytokine
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	98231.39
Authors	Carr, P.D.,Conlan, F.,Ford, S.,Ollis, D.L.,Young, I.G. (deposition date: 2006-05-09, release date: 2006-06-20, Last modification date: 2023-08-30)
Primary citation	Carr, P.D.,Conlan, F.,Ford, S.,Ollis, D.L.,Young, I.G. An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope. Acta Crystallogr.,Sect.F, 62:509-513, 2006 Cited by PubMed: 16754968 DOI: 10.1107/S1744309106016812 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation