1GH7
CRYSTAL STRUCTURE OF THE COMPLETE EXTRACELLULAR DOMAIN OF THE BETA-COMMON RECEPTOR OF IL-3, IL-5, AND GM-CSF
Summary for 1GH7
Entry DOI | 10.2210/pdb1gh7/pdb |
Descriptor | CYTOKINE RECEPTOR COMMON BETA CHAIN, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | dimer of interlocking chains of fibronectin-iii domains four fibronectin-iii domains per chain, cytokine receptor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 97939.11 |
Authors | Carr, P.D.,Gustin, S.E.,Church, A.P.,Murphy, J.M.,Ford, S.C.,Mann, D.A.,Woltring, D.M.,Walker, I.,Ollis, D.L.,Young, I.G. (deposition date: 2000-11-27, release date: 2001-11-28, Last modification date: 2023-12-27) |
Primary citation | Carr, P.D.,Gustin, S.E.,Church, A.P.,Murphy, J.M.,Ford, S.C.,Mann, D.A.,Woltring, D.M.,Walker, I.,Ollis, D.L.,Young, I.G. Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration. Cell(Cambridge,Mass.), 104:291-300, 2001 Cited by PubMed: 11207369DOI: 10.1016/S0092-8674(01)00213-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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