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1GH7

CRYSTAL STRUCTURE OF THE COMPLETE EXTRACELLULAR DOMAIN OF THE BETA-COMMON RECEPTOR OF IL-3, IL-5, AND GM-CSF

Summary for 1GH7
Entry DOI10.2210/pdb1gh7/pdb
DescriptorCYTOKINE RECEPTOR COMMON BETA CHAIN, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywordsdimer of interlocking chains of fibronectin-iii domains four fibronectin-iii domains per chain, cytokine receptor
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight97939.11
Authors
Carr, P.D.,Gustin, S.E.,Church, A.P.,Murphy, J.M.,Ford, S.C.,Mann, D.A.,Woltring, D.M.,Walker, I.,Ollis, D.L.,Young, I.G. (deposition date: 2000-11-27, release date: 2001-11-28, Last modification date: 2023-12-27)
Primary citationCarr, P.D.,Gustin, S.E.,Church, A.P.,Murphy, J.M.,Ford, S.C.,Mann, D.A.,Woltring, D.M.,Walker, I.,Ollis, D.L.,Young, I.G.
Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration.
Cell(Cambridge,Mass.), 104:291-300, 2001
Cited by
PubMed: 11207369
DOI: 10.1016/S0092-8674(01)00213-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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