2GYS
2.7 A structure of the extracellular domains of the human beta common receptor involved in IL-3, IL-5, and GM-CSF signalling
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytokine receptor common beta chain | polymer | 419 | 47812.5 | 2 | GenBank (47678387) Pfam (PF21460) UniProt (by SIFTS) (P32927) | Homo sapiens (human) | GM-CSF/IL-3/IL-5 receptor common beta-chain, CD131 antigen, CDw131 |
| 2 | C, E (C, E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 2 | In PDB GlyTouCan (G18638YB) | |||
| 3 | D, F (D, F) | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G11971MR) |
Sequence modifications
A, B: 1 - 419 (GenBank: 47678387)
| PDB | External Database | Details |
|---|---|---|
| Gln 328 | Asn 352 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 95624.9 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2606.4 | |
| All* | Total formula weight | 98231.4 |
