2FO4
Enhanced MHC class I binding and immune responses through anchor modification of the non-canonical tumor associated MUC1-8 peptide
Summary for 2FO4
Entry DOI | 10.2210/pdb2fo4/pdb |
Related | 1G7Q |
Descriptor | H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, 8-mer from Mucin-1, ... (8 entities in total) |
Functional Keywords | anchor modifications, h-2kb, muc1, non-canonical peptide, muc1-8, vaccine design, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 45506.89 |
Authors | Lazoura, E.,Ramsland, P.A. (deposition date: 2006-01-12, release date: 2006-11-14, Last modification date: 2023-10-25) |
Primary citation | Lazoura, E.,Lodding, J.,Farrugia, W.,Ramsland, P.A.,Stevens, J.,Wilson, I.A.,Pietersz, G.A.,Apostolopoulos, V. Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide Immunology, 119:306-316, 2006 Cited by PubMed: 17067310DOI: 10.1111/j.1365-2567.2006.02434.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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