2FLL
Ternary complex of human DNA polymerase iota with DNA and dTTP
Summary for 2FLL
Entry DOI | 10.2210/pdb2fll/pdb |
Related | 1T3N 2AZL 2FLN 2FLP |
Descriptor | DNA primer strand, DNA template strand, DNA polymerase iota, ... (6 entities in total) |
Functional Keywords | dna polymerase, lesion bypass, y-family, ternary complex, p6522, replication-dna complex, replication/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9UNA4 |
Total number of polymer chains | 3 |
Total formula weight | 52989.72 |
Authors | Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2006-01-06, release date: 2006-12-12, Last modification date: 2023-08-30) |
Primary citation | Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14:749-755, 2006 Cited by PubMed: 16615915DOI: 10.1016/j.str.2006.01.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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