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2FLN

binary complex of catalytic core of human DNA polymerase iota with DNA (template A)

Summary for 2FLN
Entry DOI10.2210/pdb2fln/pdb
Related1T3N 2ALZ 2FLL 2FLP
DescriptorDNA template strand, DNA primer strand, DNA polymerase iota, ... (4 entities in total)
Functional Keywordsdna polymerase, lesion bypass, binary complex, template a, replication-dna complex, replication/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus: Q9UNA4
Total number of polymer chains3
Total formula weight52458.94
Authors
Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2006-01-06, release date: 2006-12-05, Last modification date: 2023-08-30)
Primary citationNair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K.
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site.
Structure, 14:749-755, 2006
Cited by
PubMed: 16615915
DOI: 10.1016/j.str.2006.01.010
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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