2D55
Structural, physical and biological characteristics of RNA.DNA binding agent N8-actinomycin D
Replaces: 1D55Summary for 2D55
Entry DOI | 10.2210/pdb2d55/pdb |
Related | 173D 1A7Y 1A7Z 1DSC 1DSD 1FJA 1I3W 1L1V 1MNV 1OVF 1QFI 1UNJ 1UNM 209D 316D |
Related PRD ID | PRD_000001 |
Descriptor | DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3'), ACTINOMYCIN D (3 entities in total) |
Functional Keywords | actinomycin d, dactinomycin, antibiotic, anti cancer, antitumor, chromophore, depsipeptide, dna-antibiotic complex, dna/antibiotic |
Biological source | STREPTOMYCES ANTIBIOTICUS |
Total number of polymer chains | 3 |
Total formula weight | 6144.68 |
Authors | Shinomiya, M.,Chu, W.,Carlson, R.G.,Weaver, R.F.,Takusagawa, F. (deposition date: 1995-05-01, release date: 1995-10-15, Last modification date: 2024-07-10) |
Primary citation | Kamitori, S.,Takusagawa, F. Crystal Structure of the 2:1 Complex between D(Gaagcttc) and the Anticancer Drug Actinomycin D. J.Mol.Biol., 225:445-, 1992 Cited by PubMed: 1593629DOI: 10.1016/0022-2836(92)90931-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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