2AET
R304K trichodiene synthase: Complex with Mg, pyrophosphate, and (4S)-7-azabisabolene
Summary for 2AET
Entry DOI | 10.2210/pdb2aet/pdb |
Related | 1JFA 1JFG 1YYS 1YYU 2AEK 2AEL |
Descriptor | Trichodiene synthase, 1,2-ETHANEDIOL, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | pyrophosphate, terpenoid synthase fold, site-directed mutagenesis, (4s)-7-azabisabolene, lyase |
Biological source | Fusarium sporotrichioides |
Total number of polymer chains | 2 |
Total formula weight | 88418.18 |
Authors | Vedula, L.S.,Cane, D.E.,Christianson, D.W. (deposition date: 2005-07-23, release date: 2005-10-04, Last modification date: 2023-08-23) |
Primary citation | Vedula, L.S.,Cane, D.E.,Christianson, D.W. Role of arginine-304 in the diphosphate-triggered active site closure mechanism of trichodiene synthase. Biochemistry, 44:12719-12727, 2005 Cited by PubMed: 16171386DOI: 10.1021/bi0510476 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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