2AEL

R304K Trichodiene Synthase: Complex With Mg, Pyrophosphate, and (4R)-7-Azabisabolene

Summary for 2AEL

• Entry DOI: 10.2210/pdb2ael/pdb
• Related: 1JFA 1JFG 1YYR 1YYT 2AEK
• Descriptor: Trichodiene synthase, 1,2-ETHANEDIOL, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: terpenoid cyclase fold, site-directed mutant, pyrophosphate, (4r)-7-azabisabolene, lyase
• Biological source: Fusarium sporotrichioides
• Total number of polymer chains: 2
• Total formula weight: 88688.61

Authors

Vedula, L.S.,Cane, D.E.,Christianson, D.W. (deposition date: 2005-07-22, release date: 2005-10-04, Last modification date: 2023-08-23)

• Primary citation: Vedula, L.S.,Cane, D.E.,Christianson, D.W.; Role of arginine-304 in the diphosphate-triggered active site closure mechanism of trichodiene synthase.; Biochemistry, 44:12719-12727, 2005; PubMed: 16171386; DOI: 10.1021/bi0510476

Experimental method

X-RAY DIFFRACTION (2.5 Å)