2AET

R304K trichodiene synthase: Complex with Mg, pyrophosphate, and (4S)-7-azabisabolene

Summary for 2AET

Entry DOI	10.2210/pdb2aet/pdb
Related	1JFA 1JFG 1YYS 1YYU 2AEK 2AEL
Descriptor	Trichodiene synthase, 1,2-ETHANEDIOL, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	pyrophosphate, terpenoid synthase fold, site-directed mutagenesis, (4s)-7-azabisabolene, lyase
Biological source	Fusarium sporotrichioides
Total number of polymer chains	2
Total formula weight	88418.18
Authors	Vedula, L.S.,Cane, D.E.,Christianson, D.W. (deposition date: 2005-07-23, release date: 2005-10-04, Last modification date: 2023-08-23)
Primary citation	Vedula, L.S.,Cane, D.E.,Christianson, D.W. Role of arginine-304 in the diphosphate-triggered active site closure mechanism of trichodiene synthase. Biochemistry, 44:12719-12727, 2005 Cited by PubMed: 16171386 DOI: 10.1021/bi0510476 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation