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28JV

Cryo-EM structure of the human holo-TFIIH-XPC complex bound to bulky lesion-mimic DNA (consensus map)

Summary for 28JV
Entry DOI10.2210/pdb28jv/pdb
Related28JM 28JS
EMDB information56544 56551 56566
DescriptorGeneral transcription and DNA repair factor IIH helicase subunit XPB, Lysine-specific demethylase RAD23B, Centrin-2, ... (16 entities in total)
Functional Keywordsnucleotide excision repair, dna repair, helicase, transcription factor, dna binding protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains13
Total formula weight641643.69
Authors
de Martin Garrido, N.,Haste, C.A.F.,Feng, J.,Cronin, N.B.,Greber, B.J. (deposition date: 2026-02-04, release date: 2026-05-06)
Primary citationde Martin Garrido, N.,Haste, C.A.F.,Feng, J.,Cronin, N.B.,Greber, B.J.
Visualisation of stepwise de-repression of TFIIH in global-genome nucleotide excision repair
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.91 Å)
Structure validation

253795

PDB entries from 2026-05-20

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