23BD

Caspase-4 p22/p10 and human GSDMD complex

Summary for 23BD

• Entry DOI: 10.2210/pdb23bd/pdb
• EMDB information: 68825
• Descriptor: Caspase-4, Gasdermin-D (3 entities in total)
• Functional Keywords: caspase-4; gasdermin d; cryo-em; interdomain linker, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 115818.40

Authors

Luan, Y.,Mao, Y.D. (deposition date: 2026-01-30, release date: 2026-06-24)

• Primary citation: Luan, Y.,Chen, E.B.,Mao, Y.D.; Cryo-EM structures of human caspase-4 in complex with full-length gasdermin D; Structure, 2026

Experimental method

ELECTRON MICROSCOPY (3.4 Å)