1Y5X
tRNA-guanine Transglycosylase (TGT) in complex with 6-Amino-4-[2-(4-methoxyphenyl)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Summary for 1Y5X
Entry DOI | 10.2210/pdb1y5x/pdb |
Related | 1Q4W 1Q63 1Q65 1Q66 1R5Y 1S38 1Y5V 1Y5W |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 6-AMINO-4-[2-(4-METHOXYPHENYL)ETHYL]-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, ... (4 entities in total) |
Functional Keywords | transferase |
Biological source | Zymomonas mobilis |
Total number of polymer chains | 2 |
Total formula weight | 86390.55 |
Authors | Stengl, B.,Meyer, E.A.,Heine, A.,Brenk, R.,Diederich, F.,Klebe, G. (deposition date: 2004-12-03, release date: 2005-12-13, Last modification date: 2023-10-25) |
Primary citation | Stengl, B.,Meyer, E.A.,Heine, A.,Brenk, R.,Diederich, F.,Klebe, G. Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding J.Mol.Biol., 370:492-511, 2007 Cited by PubMed: 17524419DOI: 10.1016/j.jmb.2007.04.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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