1R5Y

Crystal Structure of TGT in complex with 2,6-Diamino-3H-Quinazolin-4-one Crystallized at PH 5.5

Summary for 1R5Y

• Entry DOI: 10.2210/pdb1r5y/pdb
• Related: 1PUD 1Q4W
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, 2,6-DIAMINO-3H-QUINAZOLIN-4-ONE, ... (4 entities in total)
• Functional Keywords: transferase
• Biological source: Zymomonas mobilis
• Total number of polymer chains: 1
• Total formula weight: 43167.29

Authors

Brenk, R.,Meyer, E.,Reuter, K.,Garcia, G.A.,Stubbs, M.T.,Klebe, G. (deposition date: 2003-10-13, release date: 2004-04-13, Last modification date: 2023-11-08)

• Primary citation: Brenk, R.,Meyer, E.,Reuter, K.,Stubbs, M.T.,Garcia, G.A.,Diederich, F.,Klebe, G.; Crystallographic Study of Inhibitors of tRNA-guanine Transglycosylase Suggests a New Structure-based Pharmacophore for Virtual Screening.; J.Mol.Biol., 338:55-75, 2004; PubMed: 15050823; DOI: 10.1016/j.jmb.2004.02.019

Experimental method

X-RAY DIFFRACTION (1.2 Å)